The Combinatorial Index

With the explosion of combinatorial solidphase methods access to informationhas become one of the main barriers facing a synthetic chemist who iscontemplating a... » 

With the explosion of combinatorial solidphase methods access to informationhas become one of the main barriers facing a synthetic chemist who iscontemplating a combinatorial approach to a medicinal chemistry problem. TheCombinatorial Index is an answer to that problem. This compendium of methodsfrom the primary literature provides quick and convenient access to reliablesynthetic transformations as well as information on linkers and analyticalmethods. Each synthetic procedure is preceded by a section entitledPoints ofInterestwhich highlights the strengths and weaknesses of the various studies.The index also covers the use of solutionbased synthesis for the generation ofmolecular diversity.Key Features Organized for rapid retrieval of published information on classes ofsynthetic transformations linkers and analytical methods Serves as a laboratory manual for bench chemists Includes a chapter on linkers to assist in choice of linking strategy Discusses strengths and limitations of the various methods Contains a structural index showing functional group transformations insolidphase synthesis «