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Research on the key mediator nitric oxide has increased exponentially over thelast ten years. It is now clear that in addition to its role within thecardiovascular system this mediator is also implicated in the normalphysiological function and disease pathology of several organs and systems. Anumber of the fundamental research observations are now being developed intotherapeutic principles and these are being pursued through clinical trials.This is the first work summarizing in its two volumes the quantum leap frombasic science to clinical applications emerging from this decade of research. «
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