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In the past few years there has been the increased recognition that the effectsof oxidative stress are not limited to the damage of cellular constituents.There is now evidence that reactive oxygen species ROS can alter cellfunction by acting upon the intermediates or second messengers in signaltransductions. Such effects on signaling mechanisms probably account for therole of oxidative stress in inflammation aging and cancer. This volume bringstogether internationally recognized researchers in both the major areas coveredby the book oxidative stress and signal transduction. The work is organized inthree sections. The first deals with the immediate cellular responses tooxidative stress and the production of second messengers. The second detailsthe connection between second messengers and the gene. The third part looksmore closely at the level of the gene. «
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