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The Adanced Methods series is intended for advanced undergraduates graduatestudents and established research scientists. Titles in the series are designedto cover current important areas of research in life sciences and include boththeoretical background and detailed protocols. The aim is to give researcherssufficient theory supported by references to take the given protocols andadapt them to their particular experimental systems.Gene transfer to animal cells was first achieved more than 30 years ago. Sincethen transformation technology has developed rapidly resulting in a multitudeof techniques for cell transformation and the creation of transgenic animals.As with any expanding technology it becomes difficult to keep track of all thedevelopments and to find a concise and comprehensive source of information thatexplains all the underlying principles. Gene Transfer to Animals Cellsdescribes the principles behind gene transfer technologies how gene expressionis controlled in animal cells and how advanced strategies can be used to addexchange or delete sequences from animal genomes in a conditional manner. Thefinal chapter provides an overview of all the applications of animal celltransformation in farming medicine and research. «
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