1. Introduction: the significance of radiobiology / 2. Irradiation-induced damage and the DNA damage r / 3. Cell death after irradiation – how, when and wh / 4... » 

1. Introduction: the significance of radiobiology / 2. Irradiation-induced damage and the DNA damage r / 3. Cell death after irradiation – how, when and wh / 4. Quantitating cell kill and cell survival / 5. Models of radiation response / 5. Dose-response relationships in radiotherapy / 6. LET and RBE / 7. Tumour growth and response to radiation / 8. Fractionation: the L-Q approach / 9. The L-Q approach in clinical practice / 10. Modified fractionation / 11. Time factors in normal-tissue response to radi / 12. The dose-rate effect / 13. Pathogenesis of normal-tissue side-effects / 14. The volume effect in radiotherapy / 15. The oxygen effect and fractionated radiotherap / 16. The tumour microenvironment and cellular hypox / 17. Therapeutic approaches to tumor hypoxia / 18. Combined radiotherapy and chemotherapy / 19. Retreatment tolerance of normal tissues / 20. Molecular image-guided radiotherapy with posit / 21. Molecular-targeted agents for enhancing tumour / 22. Biological response «